Dating and hookup apps (DHAs) are now widely used and may be transforming our intimate relationships. The apps are beneficial in fostering intimate connections among those who are lonely, who are members of minority or marginalized groups, or who live nomadic lifestyles because of work or recreational travel. However, the wider social and relational changes that DHAs portend are merely beginning to be seriously discussed by academics (Arias et al., 2017). In this chapter, we employ concepts from the philosophy of (...) technology that inform our analysis of these changes. We also collate some of the morally significant impacts of DHAs and present some of the elements of the architecture of DHAs that facilitate them. Although there are many reasons to be concerned about DHAs, we argue that there is room for cautious optimism that DHAs may be vehicles of positive social and moral change. (shrink)

This study was intended to determine the level of factors affecting the decision of 4th year BS Accountancy students from College of Maasin to work after graduation or to take the 2022 CPALE. In order to determine the factors affecting the decision of the graduating Accountancy students, the researchers adopted the descriptive survey design. Descriptive survey is a sort of descriptive study that uses surveys to collect data on a variety of issues. The goal of this information is to see (...) how different circumstances can be obtained among the respondents. The following results were derived in the course of the conduct of this study; There is bigger percentage of female than of male where 26 out of 27 belongs to the age group of 20 to 22. Majority of the student’s parent’s occupation status is working. Conversely, most of them only earns P2,000 to P5,000 per month even though the household member earning for a living is 1 to 4 members, the first 3 factors namely financial status, peer pressure and parent’s influence were found to slightly affect the decision of the student with regards to taking the CPALE or to work after graduation. The last factor, school’s teaching influence turned out that it somewhat affects the decision of the students, there is a significant difference between the teaching influence factor and the demographic profile of gender while on the age and parent’s occupation status, it has a significance difference with financial status factor. As BSA students taking a course where a licensure examination awaits after graduation, it is necessary to take some factors into consideration before coming up into a decision regarding taking the CPALE or to work after graduation. Based on the results of the study, the level of factors to affect the decision of the students was determined. It has been shown in the results that the three factors namely financial status, peer pressure and parent’s influence can slightly affect the student’s decision. However, among three, peer pressure has the highest weighted mean rating of 2.86. On the other hand, the school’s teaching influence has the lowest weighted mean rating of 2.29 which means it can somewhat affect the decision of the student. (shrink)

A wide variety of ontologies relevant to the biological and medical domains are available through the OBO Foundry portal, and their number is growing rapidly. Integration of these ontologies, while requiring considerable effort, is extremely desirable. However, heterogeneities in format and style pose serious obstacles to such integration. In particular, inconsistencies in naming conventions can impair the readability and navigability of ontology class hierarchies, and hinder their alignment and integration. While other sources of diversity are tremendously complex and challenging, agreeing (...) a set of common naming conventions is an achievable goal, particularly if those conventions are based on lessons drawn from pooled practical experience and surveys of community opinion. We summarize a review of existing naming conventions and highlight certain disadvantages with respect to general applicability in the biological domain. We also present the results of a survey carried out to establish which naming conventions are currently employed by OBO Foundry ontologies and to determine what their special requirements regarding the naming of entities might be. Lastly, we propose an initial set of typographic, syntactic and semantic conventions for labelling classes in OBO Foundry ontologies. Adherence to common naming conventions is more than just a matter of aesthetics. Such conventions provide guidance to ontology creators, help developers avoid flaws and inaccuracies when editing, and especially when interlinking, ontologies. Common naming conventions will also assist consumers of ontologies to more readily understand what meanings were intended by the authors of ontologies used in annotating bodies of data. (shrink)

We discuss recent progress in the development of cognitive ontologies and summarize three challenges in the coordinated development and application of these resources. Challenge 1 is to adopt a standardized definition for cognitive processes. We describe three possibilities and recommend one that is consistent with the standard view in cognitive and biomedical sciences. Challenge 2 is harmonization. Gaps and conflicts in representation must be resolved so that these resources can be combined for mark-up and interpretation of multi-modal data. Finally, Challenge (...) 3 is to test the utility of these resources for large-scale annotation of data, search and query, and knowledge discovery and integration. As term definitions are tested and revised, harmonization should enable coordinated updates across ontologies. However, the true test of these definitions will be in their community-wide adoption which will test whether they support valid inferences about psychological and neuroscientific data. (shrink)

We discuss recent progress in the development of cognitive ontologies and summarize three challenges in the coordinated development and application of these resources. Challenge 1 is to adopt a standardized definition for cognitive processes. We describe three possibilities and recommend one that is consistent with the standard view in cognitive and biomedical sciences. Challenge 2 is harmonization. Gaps and conflicts in representation must be resolved so that these resources can be combined for mark-up and interpretation of multi-modal data. Finally, Challenge (...) 3 is to test the utility of these resources for large-scale annotation of data, search and query, and knowledge discovery and integration. As term definitions are tested and revised, harmonization should enable coordinated updates across ontologies. However, the true test of these definitions will be in their community-wide adoption which will test whether they support valid inferences about psychological and neuroscientific data. (shrink)

As part of a trend in modern cognitive science, cognitive linguist, George Lakoff, and philosopher, Mark Johnson claim to provide a biologically-based account of subsymbolic meaningful experiences. They argue that human beings understand objects by extrapolating from their sensory motor activities and primary perceptions. Lakoff and Johnson’s writings have generated a good deal of interest among scholars of Early China because they maintain that “our common embodiment allows for common stable truths.” Although there are many grounds on which Lakoff and (...) Johnson’s theories have been criticized, this essay focuses in particular on problems related to their schema of Self as Container. Lakoff and Johnson contend that there are no pure experiences outside of culture, while nevertheless arguing that the experience of being a closed-off container is “direct.” “The concepts OBJECT, SUBSTANCE and CONTAINER emerge directly,” they write. “We experience ourselves as entities, separate from the rest of the world—as containers with an inside and an outside.” By “emerge directly,” they do not mean emerging free of culture, but rather that some experiences within culture, specifically physical experiences, are more directly given than others. My study explores the pitfalls of presuming the “direct” experience of containment makes good sense of texts from Early China (ca. 500–100 B.C.E). (shrink)

Background: This study tested the core tenets of how facial scars are perceived by characterizing layperson response to faces with scars. The authors predicted that scars closer to highly viewed structures of the face (i.e., upper lip and lower lid), scars aligned against resting facial tension lines, and scars in the middle of anatomical subunits of the face would be rated less favorably. Methods: -/- Volunteers aged 18 years and older from the United States were recruited through Amazon’s Mechanical Turk (...) to complete a face rating survey. Scars were digitally added in different locations and orientations for a total of 14 unique scars added to each face. Each participant rated 50 different faces on confidence, friendliness, and attractiveness. Data were analyzed using linear mixed effects models. Results: -/- A total of 88,850 ratings [82,990 scarred (93.4 percent)] for attractiveness, friendliness, and confidence were analyzed. In univariate linear mixed effects models, the presence of a facial scar did not significantly impact attractiveness (β = 0.016, SE = 0.014, z = 1.089, p = 0.276). A second set of linear mixed effects models identified interactions between location, subunit placement, and orientation to facial tension lines. Scars located on the lower lid mid subunit perpendicular to facial tension lines were rated less attractive (β = −0.065, SE = 0.028, z = −2.293, p = 0.022). Conclusions: -/- On average, a single well-healed facial scar does not negatively affect first impressions of attractiveness, confidence, or friendliness. Specific scar location and orientation combinations, however, such as a perpendicular scar at the mid-lower eyelid, may result in lower perceived attractiveness, confidence, and friendliness. (shrink)

Proza e shkurtër në këtë vëllim, e ribashkuar nën titullin „Me duar në xhepa të qepur”, tërheq konflikte midis ekzistencës dhe thelbit, duke projektuar ngërçe, aporie identitare dhe shëmbëlltyra komunikimi. 1-0 (?) është një satirë për futbollin dhe aranzhimet - në favor të skuadrave apo lojtarëve të caktuar - që u prodhuan intensivisht gjatë periudhës socialiste, të dominuara nga gënjeshtra, mistifikimi dhe faji. GIONÍ diskuton për komplekset adoleshente-adoleshente të disa krijesave me status të pasigurt, të përhumbur nga dështimi dhe dështimi, (...) të cilat autori, në frymën amerikane, i shpëton në fund, duke i dërguar në punë (pa na shpjeguar sesi do të ishte i mundur shpëtimi ontologjik). Mekanizmi epik në XHAMANTANI BOJËALLI duket i huazuar nga Mircea Eliade, i zbatuar vetëm në dimensione deterministe, ndër të cilat zbulimi I paautenticitetit të një martese është më pak problematik. Tek KU ISHA NË VEND, strategjitë e fiksionit autobiografik funksionojnë me mjeshtëri, autori rikujtues na çon nëpër labirintin e fatit drejt arratisjes në brendësi. Katër tekstet e fundit (në anglisht) janë drafte për më vonë. Një sërë ilustrimeve mbështesin tekstet dhe, në tensionin e ideve, gjarpërimet e rrëfimit të Florentin Smarandache befasojnë këndshëm, duke shkaktuar keqardhje që autori, shumë më i tërhequr nga shkenca, por edhe nga avangarda, nuk kërkonte një konservator fati letrar në prozë. Kam bindjen se do të jetë një sukses. (shrink)

_La Peste_, originally published in 1947 by the Nobel Prize-winning writer Albert Camus, chronicles the progression of deadly bubonic plague as it spreads through the quarantined Algerian city of Oran. While most discussions of fictional examples within aesthetics are either historical or hypothetical, Camus offers an example of "pestilence fiction." Camus chose fiction to convey facts--about plagues in the past, his own bout with tuberculosis at age seventeen, living under quarantine away from home for several years, and forced separation from (...) his wife who remained in Algiers while he was abroad in Nazi-occupied France. His own lived experiences undergird an imaginative account of shared human realities with which we can identify: vulnerability to the disease, isolation, fear, and finally humanitarianism. _The Plague_ teaches us to neither covet nor expect what we so casually took for granted. This collection of original essays on philosophical themes in _The Plague_ is of special relevance during and in the aftermath of Covid-19 but also provides reflections that will be of lasting value to those interested in this classic work of literature. The novel explores questions of enduring importance. Do we collectively meet the threshold of ethical behavior posed by Camus who wrote, "What's true of all the evils in the world is true of plague as well. It helps men to rise above themselves"? Or does the absurd undermine the compassionate? Do "heroes" dutifully fight a plague with "common decency," or does human nature resign itself to the normalization of uncontrollable suffering and death? There are myriad ways to approach the novel and this volume encourages readers to ponder human dilemmas in fictional Oran informed by our current pandemic. Series editor forward by Richard Eldridge. List of Contributors includes Steven G. Kellman, Jane E. Schultz, Andrew Edgar, Kathleen Higgins, Edward B. Weiser, Cynthia A. Freeland, and Margaret E. Gray; see "Introduction" by Peg Brand Weiser below. (shrink)

Epistemologists often claim that in addition to belief and disbelief there is a third, neutral, doxastic attitude. Various terms are used: ‘suspending judgment’, ‘withholding’, ‘agnosticism’. It is also common to claim that the factors relevant to the justification of these attitudes are epistemic in the narrow sense of being factors that bear on the strength or weakness of one’s epistemic position with respect to the target proposition. This paper addresses two challenges to such traditionalism about doxastic attitudes. The first concerns (...) the relevance of non-epistemic factors we might call "future-comparative" – e.g., that you’ll have more decisive evidence on whether p tomorrow – to the justification of suspending judgment. The second, from Jane Friedman, is to explain the point of the neutral attitude without appealing to inquiry and thus taking goal-related factors, which are not epistemic, such as the value of the goal or the prospects for finding means to achieve it, to bear on the justification of the neutral attitude. My defense of traditionalism relies on distinguishing three ways of being neutral on a question: agnosticism, inquiry and suspension of judgment. Traditionalism is saved because, of these, agnosticism alone is a genuine doxastic attitude. (shrink)

The goal of this paper is to argue that there is indeterminacy in causation. I present three types of cases in which it is indeterminate whether an event c caused another event e: (1) cases of absence causation recently discussed by Bernstein and by Swanson, (2) cases leading to Sorites paradoxes for causation, and (3) cases where c and e occur in certain indeterministic causal structures and it is therefore indeterminate whether there is a causal relation between them. These (...) cases, I argue, provide strong evidence that indeterminacy is an important general feature of the causal relation and that philosophical theorizing about causation should take this observation into account. (shrink)

In philosophical aesthetics, discussions on design objects place the notion of Functional Beauty at the fore. Such a philosophical approach can be found in Jane Forsey’s book The Aesthetics of Design that focuses on the notion of function to promote the aesthetic value of design and develops an interpretation of Kantian Dependent Beauty around it. Lucía Jiménez Sánchez has recently put forward several flaws of Functional Beauty accounts. She presented several practical cases as evidence for the narrowness of Functional (...) Beauty accounts. Two cases are presented against Jane Forsey’s theory of Dependent Beauty, holding that it excludes other properties from appreciation that are not necessarily related to functionality, i.e., expres- sive properties. The purpose of this article is to show that these criticisms leveled at Jane Forsey’s proposal for an aesthetic theory of design are unfounded and are based on a misun- derstanding of the structure of judgments of beauty in her system. Despite this, these criticisms highlight the need to clarify the purpose of the aesthetics of design. (shrink)

Readers assume that commonplace properties of the real world also hold in realistic fiction. They believe, for example, that the usual physical laws continue to apply. But controversy exists in theories of fiction about whether real individuals exist in the story’s world. Does Queen Victoria exist in the world of Jane Eyre, even though Victoria is not mentioned in it? The experiments we report here find that when participants are prompted to consider the world of a fictional individual (“Consider (...) the world of Jane Eyre…”), they are willing to say that a real individual (e.g., Queen Victoria) can exist in the same world. But when participants are prompted to consider the world of a real individual, they are less willing to say that a fictional individual can exist in that world. The asymmetry occurs when we ask participants both if a real person is in the character’s world and if the person would appear there. However, the effect is subject to spatial and temporal constraints. When the person and the character share spatial and temporal settings, interchange is more likely to occur. These results shed light on the author’s implicit contract with the reader, which can license the reader to augment a fictional world with features that the author only implicates as part of the work’s background. (shrink)

Wir wissen, dass eine Transformation von globalem Ausmaß bereits begonnen hat, und wir wissen, dass ihre Entfaltung nicht vorhersehbar ist. Wir können sicher sein, dass es eine Herausforderung sein wird: Wir werden inmitten tiefgreifender Veränderungen leben, unser Überleben wird ständig auf dem Spiel stehen. Werden wir das Verständnis, die Weisheit erreichen, um diese Herausforderung zu bestehen? Hier sind einige Gedanken und Überlegungen, die uns helfen, den Zustand zu erreichen, in dem wir eine positive Antwort geben können. -/- Zurückblicken, um nach (...) vorne zu sehen -/- Dies wird nicht das erste Mal in der Geschichte sein, dass für die Menschheit eine Periode der Transformation auf globaler Ebene angebrochen ist. Der Wissenschaftsphilosoph Holmes Rolston wies darauf hin, dass unsere „große Geschichte“ drei solcher Transformationen umfasst – wahre „Urknalle“.1 Die erste war der physische Urknall, der vermutlich vor etwa 13,8 Milliarden Jahren stattfand. Es gebar das manifeste Universum mit seinen Quantenteilchen, vielfältigen Arten von Energien und Milliarden von Galaxien. Es führte zur Bildung von Sonnensystemen mit Sonnen und Planeten und Energieflüssen, die die Entwicklung von lebenden (glücklich gelegenen) Planeten ermöglichen, die aktive Sonnen umkreisen. Eine weitere grundlegende Transformation – ein „zweiter Urknall“ – war die Entstehung lebender Organismen in den komplexen Systemen, die sich auf der Erde und vermutlich auch auf anderen Planeten entwickelt haben. Es wird angenommen, dass diese Transformation vor etwa 3,8 Milliarden Jahren stattgefunden hat. Es begann mit der Entstehung einzelliger Prokaryoten in der Ursuppe, die die Oberfläche des Planeten bedeckte. Der „dritte Urknall“ soll vor etwa 120.000 Jahren stattgefunden haben. Es hat das Bewusstsein unserer Spezies grundlegend verändert – „entwickelt“. Homo soll sapiens geworden sein. Zu den evolutionären Vorteilen des weiterentwickelten Bewusstseins gehörte eine flexiblere und schnellere Form der Kommunikation. Die Kommunikation war nicht mehr auf halbautomatische Reaktionen beschränkt, die durch wiederkehrende Bedingungen und Ereignisse ausgelöst wurden; Anstatt sich auf Zeichen zu beschränken, basierte die menschliche Kommunikation auf einvernehmlich entwickelten Symbolen. -/- Die Entwicklung der Symbolsprache war ein großer Sprung. Einerseits brachte es soziale Strukturen hervor, die auf kollektiv erworbener Bedeutung beruhten, und andererseits produzierte es verbesserte manipulative Fähigkeiten. Gesellschaften könnten sich auf der Grundlage gemeinsamer Kulturen entwickeln, die mächtige Technologien einsetzen. Homo sapiens begann andere Arten zu dominieren und wurde zu einem Schlüsselfaktor in der Evolution des Lebens in der Biosphäre. Der dritte Urknall erzeugte eine Explosion der menschlichen Bevölkerung, aber er brachte nicht die Weisheit hervor, die sicherstellen würde, dass die erweiterte Bevölkerung das Gleichgewicht aufrechterhalten könnte, das für das Gedeihen des Lebens auf diesem Planeten unerlässlich ist. Diese Gleichgewichte wurden immer mehr beeinträchtigt. Der kurzsichtige Einsatz von Technologie und die Missachtung natürlicher Kontrollmechanismen brachten die Menschheit dorthin, wo sie heute ist: an einen „Chaos-Punkt“, an dem die Wahl klar ist: zwischen Zusammenbruch und Durchbruch.2 Eine weitere globale Transformation ist unvermeidlich geworden und ist es noch tatsächlich im Gange: ein vierter Urknall. Es ist an der Zeit, die Lehren aus der Geschichte zu ziehen. Der Aufbau unserer Herrschaft auf dem Planeten hängt davon ab, ob wir die Herausforderung dieser Transformation meistern. -/- Die erste und grundlegende Lektion ist einfach und offensichtlich. Wir haben uns von der natürlichen Welt getrennt und müssen zurückkommen – nicht um Wilde und „Primitive“ zu werden, sondern Wesen, die auf die Welt um sie herum eingestimmt sind, die im Einklang mit den Rhythmen und Gleichgewichten der Natur leben und kompatibel erschaffen und nachhaltige eigene Rhythmen und Balancen. Wir sind nicht mehr auf die Rhythmen und Balancen der Natur ausgerichtet. Obwohl wir durch unsere biologische Evolution in diese Rhythmen und Balancen „eingebaut“ sind, haben wir unsere eigenen künstlichen Rhythmen und gefährlichen Balancen geschaffen, die die natürlichen Rhythmen ignorieren und oft mit ihnen in Konflikt stehen. Mit der Sonne aufzugehen und sich mit der Sonne zurückzuziehen bedeutet, sich an den zirkadianen 24-Stunden-Rhythmus anzupassen, der durch die Bewegung der Erde um die Sonne geschaffen wurde, und die sogenannten primitiven Menschen leben immer noch in Harmonie damit, und das tun die meisten auch die restlichen indigenen und traditionellen Kulturen. Aber moderne Menschen missachten die Rhythmen und Gleichgewichte der Natur und glauben, dass sie sie ersetzen können, indem sie Lichter und andere künstliche Annehmlichkeiten mit dem Umlegen eines Schalters ein- und ausschalten. Doch der menschliche Körper passt sich nicht den künstlichen Rhythmen an, und wir leiden unter den Folgen. -/- 3Die Wirksamkeit des Immunsystems ist beeinträchtigt, und trotz einer Flut von biochemischen Medikamenten breiten sich Krankheiten aus. Moderne Bevölkerungen sind Stadtbewohner und haben nur begrenzten Kontakt mit der Natur. Sie leben in einer künstlichen Welt und denken, dass es die reale Welt ist. Sie halten sich anderen Lebensformen überlegen und glauben, die Natur nach Belieben beherrschen zu können. Noch vor fünfzig Jahren musste die Tierintelligenzforscherin Jane Goodall gegen die damals noch vorherrschende Überzeugung ankämpfen, dass ChiMenschen sind biochemische Reiz-Reaktions-Mechanismen, keine lebenden und fühlenden Wesen. Heute erkennen wir, dass nicht nur höhere Säugetiere, alle lebenden Organismen und sogar Bäume und Pflanzen sensible Lebewesen sind und sich in dieser Hinsicht nicht grundlegend von uns unterscheiden. Es liegt im besten Interesse unseres körperlichen und geistigen Wohlbefindens, dass wir diese Missverständnisse und fehlerhaften Verhaltensweisen korrigieren. Wenn wir dies tun, gewinnen wir unsere natürliche Gesundheit und Vitalität zurück. Die heilende Wirkung natürlicher Substanzen und Lebensweisen war schon in der Antike Heilern und Weisen bekannt. Seit Hippokrates, der als Vater der modernen Medizin gilt, suchen Mediziner nach Substanzen und Methoden, die das Gleichgewicht und die Verbindung zwischen Mensch und Natur wiederherstellen. Heute wird dieser Anspruch überschattet von einer oft kommerziell motivierten Abhängigkeit von synthetischen Substanzen und naturverachtenden Praktiken. Die Szene ist nicht nur negativ: Wie wir sehen werden, gibt es positive Entwicklungen in allen Bereichen des menschlichen Strebens, einschließlich Heilung und Medizin. Die Verbindung mit der Natur ist ein Hauptziel der alternativen Heilmethoden, die als Informations- und Energiemedizin bekannt sind. Diese Form der Heilung erlebt in verschiedenen Teilen der Welt, vor allem im Orient, eine Renaissance. Shirin yoku, die japanische Kunst des Waldbadens, ist ein Paradebeispiel. Um es zu praktizieren, müssen wir in einen Wald gehen und uns auf seine Rhythmen und Energien eingestimmt fühlen – den Wind durch die Blätter rauschen hören, das Lichtspiel auf der Oberfläche eines Teichs spüren, mit den Wolken schweben, wenn sie sich durch den Himmel bewegen. Psychotherapeuten finden, dass sogar die Geräusche der Natur, das Zwitschern der Vögel, das Rauschen der Bäche heilend wirken. Einfach in einem Wald zu sein oder neben einem Baum zu stehen, beruhigt und heilt das Nervensystem. Eine weitere wesentliche Aufgabe ist es, positive Entwicklungen in der Gesellschaft zu erkennen und daran anzuknüpfen. -/- Es gibt positive Entwicklungen in der Gesellschaft, und es gibt gesunde, lebensspendende und erhaltende Prozesse in der Natur. Wir könnten wieder in die Natur eintauchen und an positiven Entwicklungen in der Gesellschaft teilhaben. Und doch gelingt uns das nicht. Wir beschreiten einen Weg, der eher zum Zusammenbruch als zum Durchbruch führt. Wir müssen überdenken, wie wir gehen, und vor allem, wohin wir gehen. Wir sind eine von mehr als hundert Millionen Arten in der Biosphäre, wobei jede Art Millionen und in einigen Fällen Milliarden von Individuen umfasst. Unter all diesen Arten und Individuen befinden wir uns in einer privilegierten Position: Wir haben ein hoch entwickeltes Gehirn und Bewusstsein. Dies ermöglicht uns zu fragen, wer wir sind, was die Welt ist und wie wir in der Welt leben können und sollen. Ein fortgeschrittenes Bewusstsein ist eine einzigartige Ressource, und wir machen keinen guten Gebrauch davon. Wir stellen nicht die richtigen Fragen und suchen nicht nach den richtigen Antworten, sondern gehen einfach vorwärts und vertrauen auf das Glück. Wir haben unsere Zahl erhöht, aber nicht die Vorteile, die unser Bewusstsein denen verleihen könnte, die wir in die Welt bringen. Wir haben ausgeklügelte Technologien entwickelt und angewendet, um unseren Bedürfnissen und Wünschen gerecht zu werden, haben aber die Mehrheit der fortgeschrittenen Arten beschädigt oder zum Aussterben gebracht. Fünfzig Prozent aller Wildtiere auf dem Planeten sind verschwunden, und jeden Tag verschwinden vierundvierzigtausend Populationen lebender Arten. Wir sind zu einer Gefahr für das Leben in der Biosphäre geworden. Die Geschichte lehrt uns, dass Urknalle, globale Transformationen, nicht unbedingt eine gerechte und blühende Welt hervorbringen; sie können zu einem Zusammenbruch führen. Wir haben die Schwelle eines vierten Urknalls erreicht, und wir tun nicht, was wir können, um einen Zusammenbruch abzuwenden. Der Großteil der heutigen Bevölkerung ist frustriert und depressiv und wird gewalttätig. Menschen leiden unter einer veränderten -/- über Klima, Umweltverschmutzung und unzählige Formen der Umweltzerstörung. Millionen durchstreifen den Planeten auf der Suche nach einem Ort, an dem sie nur überleben können. Die Lehren der Geschichte liegen vor uns, und wir ignorieren sie. Dennoch könnten wir die Lektionen lernen und unsere Wege korrigieren. Wir sind durchaus in der Lage, auf diesem Planeten zu leben, ohne das Gleichgewicht und die Ressourcen zu zerstören, die für ein gesundes Leben für uns und andere Arten erforderlich sind. Keine Spezies müsste dezimiert, unterworfen oder zum Aussterben getrieben werden, um uns am Leben zu erhalten. Wir könnten nachhaltig leben, mit anderen Arten koexistieren und die Grenzen des Lebens auf dem Planeten respektieren. Wir könnten die Verfügbarkeit lebenswichtiger Ressourcen für alle Menschen und Bevölkerungsgruppen sicherstellen. Dennoch treiben wir unzählige Arten zum Aussterben und schädigen die gemeinsame Umwelt. Die bloße Tatsache, dass wir es geschafft haben, als biologische Spezies fünf Millionen Jahre und als bewusste Spezies fünfzigtausend Jahre zu überleben, ist ein Beweis dafür, dass unsere grundlegende Natur nicht das Problem ist. Es ist nicht die Masse der menschlichen Bevölkerung, die dafür verantwortlich ist, zu einer Geißel des Lebens auf dem Planeten zu werden, sondern nur ein Teil. Die Frage ist, warum dieses Segment unhaltbare und jetzt kritische Bedingungen für geschaffen hat die höheren Formen des Lebens auf der Erde? Und kann es sich rechtzeitig ändern und transformieren, um eine große Katastrophe zu vermeiden? Theologische und mystische Annahmen wurden manchmal als Grund dafür angeführt, dass wir zu dem wurden, was wir sind, aber unser Verhalten göttlichen oder anderen transzendenten Ursachen zuzuschreiben, ist nicht die Antwort. Wir sind weder Engel noch Teufel. Wir wurden zur Geißel, zu der wir unbeabsichtigt geworden sind. Zu Beginn des Neolithikums begann ein Teil der Menschheit, die Ressourcen des Planeten ohne Rücksicht auf irgendetwas und irgendjemanden zu nutzen und sich nur darauf zu konzentrieren, seinen eigenen Komfort und seine eigene Macht zu verbessern. Auf einem endlichen und voneinander abhängigen Planeten führte dies zu unausgewogenen und unhaltbaren Bedingungen. Der egozentrische Umgang mit Ressourcen hat das Netz des Lebens beschädigt. Die menschliche Spezies wurde zu einer Bedrohung für alles Leben auf dem Planeten und auch für sich selbst: Die Gesundheit des Netzes des Lebens ist eine Vorbedingung für die Gesundheit der dort lebenden Spezies. Dies ist eine relativ junge Erkenntnis. Jahrtausendelang gingen die Menschen ihren Daseinsaufgaben nach, ohne sich bewusst zu sein, dass die unreflektierte Verfolgung ihrer eigenen Interessen um sie herum zum Fluch des Lebens wird. -/- Wir sind zu einem Fluch für das Leben auf diesem Planeten geworden; Wir haben die Welt zu einem Spielzeugladen gemacht, in dem wir die leistungsstarken Spielzeuge bauen, die unseren wahrgenommenen Interessen dienen. Wir spielen mit unseren Spielsachen unabhängig davon, ob sie wirklich unseren Bedürfnissen dienen, und ohne Rücksicht auf die Bedürfnisse anderer. Wir setzen die Energie des Atoms frei und nutzen sie, um Systeme anzutreiben, die unsere Bedürfnisse befriedigen. Wir leiten Elektronenströme in integrierte Schaltkreise und verwenden die Schaltkreise, um die Technologien zu beherrschen, die unseren Anforderungen an Kommunikation und Information dienen. Wir spielen im globalen Spielzeugladen ohne Rücksicht auf die Folgen für andere und für den gesamten Laden. Dies ist ein kurzsichtiges und gefährliches Verhalten. Wir greifen auf Energie auf eine Weise zu, die nicht unseren wirklichen Bedürfnissen dient, sondern nur unseren kurzfristigen, egozentrischen Bedürfnissen. Ähnlich kurzsichtig manipulieren wir Informationen. Beispiele dafür sind die Atombombe und das Atomkraftwerk auf der einen Seite und der Computer mit seinem Netzwerk aus globalem Geschwätz auf der anderen Seite. Atomkraft, selbst für friedliche Zwecke, und künstliche Intelligenz, selbst wenn sie gut gemeint ist, sind gefährliche Spielzeuge. Sie können zu technologischen Überschreitungen werden, die am Ende unser Leben und das gesamte Lebensnetz in der Biosphäre schädigen. Wir sind an sich gut, aber egozentrisch und kurzsichtig. Aber das kann nicht unwidersprochen bleiben. Die Zeit, in der wir naiv mit mächtigen Spielzeugen spielen konnten, ist vorbei. Ihre unvorhergesehenen „Nebenwirkungen“ sind zu einer Bedrohung für alles Leben auf dem Planeten geworden, einschließlich unseres eigenen. -/- Vorwärts gehen. -/- Wir sind an der Schwelle des vierten Urknalls angekommen. Was machen wir jetzt? Wenn wir gedeihen oder auch nur überleben wollen, muss sich unser Bewusstsein ändern. Gelingt dies nicht, wird der nächste Urknall unser letzter sein. Eine globale Transformation ist ein riskanter Prozess: Soll sie nicht zum Zusammenbruch, sondern zum Durchbruch führen, muss sie gesteuert werden. Wir können mit der bewussten Führung unserer Evolution beginnen, indem wir Gandhis Rat folgen: Sag anderen nicht, was sie tun sollen; Werde du selbst zu dem, was sie und die Welt werden sollen. Unsere wesentliche Aufgabe ist es, die Transformation der Welt zu werden. Wir müssen Ausdruck eines reifen und gesunden Lebens in der Biosphäre sein. Wenn diese kritische Masse erreicht wird, wird der „vierte Urknall“ nicht das Ende des Lebens auf dem Planeten markieren. Es wird eine disruptive globale Transformation sein, aber keine destruktive. Es wird eine neue Phase in der Amtszeit der Menschheit auf dem Planeten auslösen und nicht das Ende dieser Amtszeit. Es ist an der Zeit, die Lehren aus der Geschichte zu ziehen – zurückzublicken, um nach vorne zu sehen. Das Überleben einer fortgeschrittenen Spezies und die Zukunft des Lebensnetzes auf diesem Planeten liegt in unseren Händen. Noch nie waren so viele von der Weisheit so weniger abhängig. Wir müssen erwachen – um erwachsen zu werden. Die Kraft des Bewusstseins zu nutzen, die in unseren Händen liegt. Es ist nicht an der Zeit zu fragen, ob wir den vierten Urknall, die bereits begonnene globale Transformation, überstehen werden. Es ist an der Zeit, sich daran zu machen, es zu schaffen. (shrink)

O renascimento do pragmatismo foi acompanhado por uma série de filósofas feministas que se esforçaram para resgatar do esquecimento as pensadoras que fizeram parte do movimento pragmatista clássico do final do século XIX e primeira metade do século XX. O presente trabalho visa introduzir aos leitores de língua portuguesa esse trabalho a partir de uma breve exposição das pensadoras Jane Addams, Mary Parker Follet, Charlotte Perkins Gilman, Mary Whiton Calkins e Ella Flagg Young.

Recent work in the philosophy of biology argues that we must rethink the biological individual beyond the boundary of the species, given that a key part of our essential functioning is carried out by the bacteria in our intestines in a way that challenges any strictly genetic account of what is involved for the biological human. The gut is a kind of ambiguous other within our understanding of ourselves, particularly when we also consider the status of gastro-intestinal disorders. Hegel offers (...) us theoretical tools to describe and understand our relationship to our gut. His description of our selves as continually mediated through otherness is strikingly compatible with the kind of structure contemporary biology presents us with. His accounts of digestion and habit, contextualized by his logic, help point toward an understanding of selfhood as porous and yet still capable of being sufficiently unified for us to make sense of ourselves, one which allows us to acknowledge otherness within us while still having enough unity for agency. (shrink)

Two major lines of argument support the notion that Hildegard of Bingen’s metaphysics is peculiarly gynocentric. Contra the standard commentary on her work, the focus is not on the notion of viriditas; rather, the first line of argument presents a specific delineation of her ontology, demonstrating that it is a graded hierarchy of beings, many of which present feminine aspects of the divine, and all of which establish the metaphysical notion of interpenetrability. The second line of argument specifically contrasts her (...) thought to that of Aquinas and Meister Eckhart, noting areas of similarity and difference. It is concluded that the visionary origins of Hildegard’s work may have to some extent precluded our understanding of it, and that her work merits consideration not only philosophically and theologically but from the standpoint of its early presentation of a gynocentric worldview. (shrink)

A discussion of L.A. Paul's 'Transformative Experience' from an Author Meets Critics session at the 2015 Pacific APA.

When discussing the problem of evil, philosophers often distinguish between physical evil (harm caused within the natural world such as natural disasters, disease, and the like), and moral evil (harm caused by human agency). Mapping this traditional distinction is mapped onto the third section of Fichte’s The Vocation of Man would at first seem fairly straightforward: for Fichte, evil arising from nature occurs through “blind mechanism” and is unfree; in contrast, evil done by human beings arises out of free agency. (...) The answer may be more complicated, however, in two different ways. First, Fichte holds that nature is to be cultivated and controlled by human beings so that it is no longer a source of harm; this may imply that the continuing harm done by nature is the result of humans’ failure to have sufficiently tamed nature. In that case, some of the harm caused by nature may be attributable to free human causality and thus no longer be a clearcut instance of natural evil. Second, Fichte repeatedly states that those who fail to act morally and who fail to conform their wills to the moral law are still be in the power of the mechanisms of nature. Even though we must think of them as free, Fichte compares their actions to the operation of nature and its mechanism of necessity. By presenting a careful and nuanced Fichtean account of the traditional distinction between physical and moral evil, we can better appreciate how Fichte understood the meaning and scope of human responsibility. (shrink)

Three professors reflect on the experience of creating a learning community of 22 students by linking courses in Literature and Ethics. The project demonstrates practical strategies for incorporating feminist scholarship and pedagogy into the core curriculum and for integrating core courses from diverse disciplines.

Michelle’s thesis explores the extent to which a researcher could contribute to change by engaging leaders in conversations that might intensify commitment to or the direction of their actions around socio-environmental decline in Bermuda as a country historically organised in the tradition of an entrepreneurial for-profit enterprise. The framing of a space to reflect on highlighted the significance of time that led to the bricolage design of a heuristic device called a moon gate. Time, the keystone of the moon gate, (...) created a prism lighting up the twists and turns of kaleidoscopic images of the chaos of the markets and the creative diversity of human and nonhuman participants. She undertook a philosophical approach with her study of the contested space of time around sensitivity to maintaining a fulcrum point based on the wellbeing of people and planet. (shrink)

Translation of "Von der Armut am Geiste; ein Dialog des jungen Lukács," by Ágnes Heller. This translation originally appeared in The Philosophical Forum, Spring-Summer 1972.

This paper explores the role of generics in social cognition. First, we explore the nature and effects of the most common form of generics about social kinds. Second, we discuss the nature and effects of a less common but equally important form of generics about social kinds. Finally, we consider the implications of this discussion for how we ought to use language about the social world.

A minimal truthmaker for a given proposition is the smallest portion of reality which makes this proposition true. Minimal truthmakers are frequently mentioned in the literature, but there has been no systematic account of what they are or of their importance. In this article we shall clarify the notion of a minimal truthmaker and argue that there is reason to think that at least some propositions have minimal truthmakers. We shall then argue that the notion can play a useful role (...) in truthmaker theory, by helping to explain the truth of certain propositions as precisely as possible. (shrink)

A growing body of research has examined how people judge the persistence of identity over time—that is, how they decide that a particular individual is the same entity from one time to the next. While a great deal of progress has been made in understanding the types of features that people typically consider when making such judgments, to date, existing work has not explored how these judgments may be shaped by normative considerations. The present studies demonstrate that normative beliefs do (...) appear to play an important role in people's beliefs about persistence. Specifically, people are more likely to judge that the identity of a given entity remains the same when its features improve than when its features deteriorate. Study 1 provides a basic demonstration of this effect. Study 2 shows that this effect is moderated by individual differences in normative beliefs. Study 3 examines the underlying mechanism, which is the belief that, in general, various entities are essentially good. Study 4 directly manipulates beliefs about essence to show that the positivity bias regarding essences is causally responsible for the effect. (shrink)

We argue that generic generalizations about racial groups are pernicious in what they communicate (both to members of that racial group and to members of other racial groups), and may be central to the construction of social categories like racial groups. We then consider how we should change and challenge uses of generic generalizations about racial groups.

ABSTRACT Temporal dynamists argue that we should believe that there exists temporal passage because there being passage is the best explanation for the presence of our temporal phenomenology. Presentists argue that presentism is the best version of temporal dynamism. Therefore, conditional on us accepting temporal dynamism, we should accept presentism. In this paper it is argued that if we understand temporal passage as the presentist does, such an argument can succeed only if dualism is true. Thus, we conclude, either presentists (...) should embrace dualism, or they should reject any argument for presentism that proceeds via any such argument for temporal passage that proceeds via considerations of what best explains our temporal phenomenology. (shrink)

Background: Facial proportionality and symmetry are positively associated with perceived levels of facial attractiveness. -/- Objective: The aims of this study were to confirm and extend the association of proportionality with perceived levels of attractiveness and character traits and determine differences in attractiveness and character ratings between "anomalous" and "typical" faces using a large dataset. -/- Methods: Ratings of 597 unique individuals from the Chicago Face Database were used. A formula was developed as a proxy of relative horizontal proportionality, where (...) a proportionality score of "0" indicated perfect proportionality and more negative scores indicated less proportionality. Faces were categorized as "anomalous" or "typical" by 2 independent reviewers based on physical features. -/- Results: Across the ratings for all faces, Spearman correlations revealed greater proportionality was associated with attractiveness ( ρ = 0.292, P < 0.001) and trustworthiness ( ρ = 0.193, P < 0.001), while lesser proportionality was associated with impressions of anger (ρ = 0.132, P = 0.001), dominance (ρ = 0.259, P < 0.001), and threateningness ( ρ = 0.234, P < 0.001). Mann-Whitney U tests revealed the typical cohort had significantly higher levels of proportionality (-13.98 versus -15.14, P = 0.030) and ratings of attractiveness (3.39 versus 2.99, P < 0.001) and trustworthiness (3.48 versus 3.35, P < 0.001). -/- Conclusions: This study demonstrated that facial proportionality is not only significantly associated with higher ratings of attractiveness, but also associated with judgements of trustworthiness. Proportionality plays a role in evoking negative attributions of personality characteristics to people with facial anomalies. (shrink)

The aim of this paper is to provide a conceptual framework that will help in understanding and evaluating, along social and ethical lines, the issue of killing day-old male chicks and two alternative directions of responsible innovations to solve this issue. The following research questions are addressed: Why is the killing of day-old chicks morally problematic? Are the proposed alternatives morally sound? To what extent do the alternatives lead to responsible innovation? The conceptual framework demonstrates clearly that there is a (...) moral “lock-in”, and why the killing of day-old chicks is indeed an issue. Furthermore, it is shown that both alternative directions address some important objections with regard to the killing of day-old chicks, but that they also raise new dilemmas. It also becomes clear that the framework enables and secures anticipation, reflection, deliberation with and responsiveness to stakeholders, the four dimensions of responsible innovation, in a structured way. (shrink)

Background: Facial attractiveness influences our perceptions of others, with beautiful faces reaping societal rewards and anomalous faces encountering penalties. The purpose of this study was to determine associations of visual attention with bias and social dispositions toward people with facial anomalies. -/- Methods: Sixty subjects completed tests evaluating implicit bias, explicit bias, and social dispositions before viewing publicly available images of preoperative and postoperative patients with hemifacial microsomia. Eye-tracking was used to register visual fixations. -/- Results: Participants with higher implicit (...) bias scores fixated significantly less on the cheek and ear region preoperatively (P = 0.004). Participants with higher scores in empathic concern and perspective taking fixated more on the forehead and orbit preoperatively (P = 0.045) and nose and lips (P = 0.027) preoperativel. -/- Conclusions: Participants with higher levels of implicit bias spent less visual attention on anomalous facial anatomy, whereas participants with higher levels of empathic concern and perspective taking spent more visual attention on normal facial anatomy. Levels of bias and social dispositions such as empathy may predict layperson gaze patterns toward those with facial anomalies and provide insights to neural mechanisms underlying the "anomalous is bad" paradigm. (shrink)

Ang mga pelikula ng viva max ay namayagpag mula ng magkaroon ng lockdown sa Pilipinas. Sa yugtong ito, nagpalabas ang viva films ng mga pelikula sa pamamagitan ng aplikasyong viva max. Sa panonood ng mga pelikula rito, kailangan mag-subscribe ng manonood. Ang pinakamababng subscription nito ay 149.00. Sa plan na ito, isang buwan ng makakapanood ang subscriber ng lahat ng pelikula ng viva max. Nilalayon ng pananaliksik na ito na talakayin ang kalagayan ng kababaihang gumaganap sa mga piling pelikula ng (...) viva max batay sa kanilang katangian at maging ang papel sa lipunan gamit ang lenteng feminismo. Gumamit ang mananaliksik ng thematic analysis. Sa paggamit ng metodong ito, masusing pinag-aralan at binigyang-kahulugan ang mga impormasyon at datos na susuriin. Naging sandigan din ng pananaliksik na ito ang teoryang feminismo kung saan sinuri ang katangian at papel na ginampanan ng bawat tauhang babae sa mga piling pelikula ng viva max upang mabigyang-linaw ang pagbabagong naganap sa kanilang katauhan. Maging ang dahilan nang patuloy na pagtangkilik ng mga manonood sa ganitong uri ng palabas sa kabila ng iba-ibang palabas na matatagpuan sa ilang aplikasyong katulad ng Netflix, Iflix at Disney. Hindi maikakaila na malaki pa rin ang hatak ng mga pelikula na mapapanood sa viva max. Makikita rin sa pananaliksik na ito ang iba-ibang katangian at kakayahan ng mga kababaihan na tiyak na hahangaan ng sinumang manonood. Mga katangiang hindi binibigyang pansin ng ilang manonood lalo na ng mga kalalakihan ngunit kung susuriin, ito ay nagpapakita ng mahahalagang aral na tiyak na kapupulutan ng aral. Mahalagang talakayin ang ganitong uri ng pananaliksik upang magbigay- linaw kung bakit patuloy itong tinatangkilik sa paglipas ng panahon sa kabila ng paglabas ng mga bagong panoorin. (shrink)

In this paper two systems of AGM-like Paraconsistent Belief Revision are overviewed, both defined over Logics of Formal Inconsistency (LFIs) due to the possibility of defining a formal consistency operator within these logics. The AGM° system is strongly based on this operator and internalize the notion of formal consistency in the explicit constructions and postulates. Alternatively, the AGMp system uses the AGM-compliance of LFIs and thus assumes a wider notion of paraconsistency - not necessarily related to the notion of formal (...) consistency. (shrink)

Richard Rorty’s conception of literature has been criticised more than acclaimed. While Rorty certainly has impacted literary studies, a comprehensive account of his understanding of literature is still lacking. Moreover, while literature is seen as significant to his later work, the philosophical role this plays in Rortyan thought is underexamined and underappreciated. This paper aims to provide an account of the role of literature and the “literary” in Rorty’s philosophy and the functions he assigns to literature and poetry – in (...) a broad and narrow sense – in democratic cultures. Beginning with an account of Rorty’s conceptions of metaphor and “unfamiliar” language, it draws on this to explain Rorty’s parallel view of literature in the “narrower sense” as playing the same role in culture as metaphors do in language. “Stimulating” literature unsettles settled selves and beliefs and expands human imagination. Using Rorty’s readings of Lolita and 1984 as examples, it shows that to him, literature not only plays a part in increasing empathy and solidarity but has a distinct therapeutic epistemological task: it helps individuals and societies adopt a more pluralist, ironist, post-metaphysical outlook. Both are important democratic functions. For these reasons, Rorty recommends that we work to realise a “literary” culture that rejects any ontologically inflected distinctions between kinds of texts, where philosophy becomes comparative “literary” criticism, and we see literature in the “narrower sense” as equally necessary material for making selves, communities and just institutions as any philosophical or political treatise. (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

In real-time, Twitter strongly imprints world events, popular culture, and the day-to-day; Twitter records an ever growing compendium of language use and change; and Twitter has been shown to enable certain kinds of prediction. Vitally, and absent from many standard corpora such as books and news archives, Twitter also encodes popularity and spreading through retweets. Here, we describe Storywrangler, an ongoing, day-scale curation of over 100 billion tweets containing around 1 trillion 1-grams from 2008 to 2020. For each day, we (...) break tweets into 1-, 2-, and 3-grams across 150+ languages, record usage frequencies, and generate Zipf distributions. We make the data set available through an interactive time series viewer, and as downloadable time series and daily distributions. We showcase a few examples of the many possible avenues of study we aim to enable including how social amplification can be visualized through ‘contagiograms’. (shrink)

Wittgenstein’s concepts shed light on the phenomenon of schizophrenia in at least three different ways: with a view to empathy, scientific explanation, or philosophical clarification. I consider two different “positive” wittgensteinian accounts―Campbell’s idea that delusions involve a mechanism of which different framework propositions are parts, Sass’ proposal that the schizophrenic patient can be described as a solipsist, and a Rhodes’ and Gipp’s account, where epistemic aspects of schizophrenia are explained as failures in the ordinary background of certainties. I argue that (...) none of them amounts to empathic-phenomenological understanding, but they provide examples of how philosophical concepts can contribute to scientific explanation, and to philosophical clarification respectively. (shrink)

This chapter provides summaries of the chapter of this book and introduces the major themes and debates addressed in the volume. Discussed are Nietzsche’s metaphysics; his philosophy of mind in light of contemporary views; the question of panpsychism of Beyond Good and Evil 36; the rejection of dualism in favour of monism, in particular a monism of value; Nietzsche’s positions on consciousness and embodied cognition in light of recent cognitive science; a conception of freedom and agency based on an intrinsically (...) motivating; embodied sense of self-efficacy; a Nietzschean account of valuing understood as drive-induced affective orientations of which an agent approves; the idea of ressentiment conceived as a process of intentional, not reflectively strategic, self-deception about one’s own conscious mental states; and a defence of a Nietzschean naturalism. (shrink)

The INBIOSA project brings together a group of experts across many disciplines who believe that science requires a revolutionary transformative step in order to address many of the vexing challenges presented by the world. It is INBIOSA’s purpose to enable the focused collaboration of an interdisciplinary community of original thinkers. This paper sets out the case for support for this effort. The focus of the transformative research program proposal is biology-centric. We admit that biology to date has been more fact-oriented (...) and less theoretical than physics. However, the key leverageable idea is that careful extension of the science of living systems can be more effectively applied to some of our most vexing modern problems than the prevailing scheme, derived from abstractions in physics. While these have some universal application and demonstrate computational advantages, they are not theoretically mandated for the living. A new set of mathematical abstractions derived from biology can now be similarly extended. This is made possible by leveraging new formal tools to understand abstraction and enable computability. [The latter has a much expanded meaning in our context from the one known and used in computer science and biology today, that is "by rote algorithmic means", since it is not known if a living system is computable in this sense (Mossio et al., 2009).] Two major challenges constitute the effort. The first challenge is to design an original general system of abstractions within the biological domain. The initial issue is descriptive leading to the explanatory. There has not yet been a serious formal examination of the abstractions of the biological domain. What is used today is an amalgam; much is inherited from physics (via the bridging abstractions of chemistry) and there are many new abstractions from advances in mathematics (incentivized by the need for more capable computational analyses). Interspersed are abstractions, concepts and underlying assumptions “native” to biology and distinct from the mechanical language of physics and computation as we know them. A pressing agenda should be to single out the most concrete and at the same time the most fundamental process-units in biology and to recruit them into the descriptive domain. Therefore, the first challenge is to build a coherent formal system of abstractions and operations that is truly native to living systems. Nothing will be thrown away, but many common methods will be philosophically recast, just as in physics relativity subsumed and reinterpreted Newtonian mechanics. -/- This step is required because we need a comprehensible, formal system to apply in many domains. Emphasis should be placed on the distinction between multi-perspective analysis and synthesis and on what could be the basic terms or tools needed. The second challenge is relatively simple: the actual application of this set of biology-centric ways and means to cross-disciplinary problems. In its early stages, this will seem to be a “new science”. This White Paper sets out the case of continuing support of Information and Communication Technology (ICT) for transformative research in biology and information processing centered on paradigm changes in the epistemological, ontological, mathematical and computational bases of the science of living systems. Today, curiously, living systems cannot be said to be anything more than dissipative structures organized internally by genetic information. There is not anything substantially different from abiotic systems other than the empirical nature of their robustness. We believe that there are other new and unique properties and patterns comprehensible at this bio-logical level. The report lays out a fundamental set of approaches to articulate these properties and patterns, and is composed as follows. -/- Sections 1 through 4 (preamble, introduction, motivation and major biomathematical problems) are incipient. Section 5 describes the issues affecting Integral Biomathics and Section 6 -- the aspects of the Grand Challenge we face with this project. Section 7 contemplates the effort to formalize a General Theory of Living Systems (GTLS) from what we have today. The goal is to have a formal system, equivalent to that which exists in the physics community. Here we define how to perceive the role of time in biology. Section 8 describes the initial efforts to apply this general theory of living systems in many domains, with special emphasis on crossdisciplinary problems and multiple domains spanning both “hard” and “soft” sciences. The expected result is a coherent collection of integrated mathematical techniques. Section 9 discusses the first two test cases, project proposals, of our approach. They are designed to demonstrate the ability of our approach to address “wicked problems” which span across physics, chemistry, biology, societies and societal dynamics. The solutions require integrated measurable results at multiple levels known as “grand challenges” to existing methods. Finally, Section 10 adheres to an appeal for action, advocating the necessity for further long-term support of the INBIOSA program. -/- The report is concluded with preliminary non-exclusive list of challenging research themes to address, as well as required administrative actions. The efforts described in the ten sections of this White Paper will proceed concurrently. Collectively, they describe a program that can be managed and measured as it progresses. (shrink)

Initial responses to questionnaires used to assess participants' understanding of informed consent for malaria vaccine trials conducted in the United States and Mali were tallied. Total scores were analyzed by age, sex, literacy (if known), and location. Ninety-two percent (92%) of answers by United States participants and 85% of answers by Malian participants were correct. Questions more likely to be answered incorrectly in Mali related to risk, and to the type of vaccine. For adult participants, independent predictors of higher scores (...) were younger age and female sex in the United States, and male sex in Mali. Scores in the United States were higher than in Mali (P = 0.005). Despite this difference participants at both sites were well informed overall. Although interpretation must be qualified because questionnaires were not intended as research tools and were not standardized among sites, these results do not support concerns about systematic low understanding among research participants in developing versus developed countries. (shrink)

Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across many key fields in biology, including genomics, systems biology, development, medicine, evolution, ecology, and systematics. Here we survey the current phenomics landscape, including data resources and handling, and the progress that (...) has been made to accurately capture relevant data descriptions for phenotypes. We present an example of the kind of integration across domains that computable phenotypes would enable, and we call upon the broader biology community, publishers, and relevant funding agencies to support efforts to surmount today's data barriers and facilitate analytical reproducibility. (shrink)

Ontology is one strategy for promoting interoperability of heterogeneous data through consistent tagging. An ontology is a controlled structured vocabulary consisting of general terms (such as “cell” or “image” or “tissue” or “microscope”) that form the basis for such tagging. These terms are designed to represent the types of entities in the domain of reality that the ontology has been devised to capture; the terms are provided with logical defi nitions thereby also supporting reasoning over the tagged data. Aim: This (...) paper provides a survey of the biomedical imaging ontologies that have been developed thus far. It outlines the challenges, particularly faced by ontologies in the fields of histopathological imaging and image analysis, and suggests a strategy for addressing these challenges in the example domain of quantitative histopathology imaging. The ultimate goal is to support the multiscale understanding of disease that comes from using interoperable ontologies to integrate imaging data with clinical and genomics data. (shrink)

In this paper we propose a very general de nition of combination of logics by means of the concept of sheaves of logics. We first discuss some properties of this general definition and list some problems, as well as connections to related work. As applications of our abstract setting, we show that the notion of possible-translations semantics, introduced in previous papers by the first author, can be described in categorial terms. Possible-translations semantics constitute illustrative cases, since they provide a new (...) semantical account for abstract logical systems, particularly for many-valued and paraconsistent logics. (shrink)

Ask most philosophers for an example of a moral rationalist, and they will probably answer “Kant.” And no wonder. Kant’s first great work of moral philosophy, Groundwork of the Metaphysics of Morals, opens with a clarion call for rationalism, proclaiming the need to work out for once a pure moral philosophy, a metaphysics of morals. That this metaphysics includes the first principle of ethics, the moral law, is obvious. But what about the second principles, particular moral laws, such as duties (...) of truthfulness, beneficence, etc.? Are these principles metaphysical too? Many have thought not, since they make essential use of empirical and anthropological considerations. I argue otherwise; the second principles are metaphysical and this matters. I do this by taking seriously the metaphysics of the metaphysics of morals—more specifically, by understanding the metaphysics of morals alongside the metaphysics of nature. For, qua metaphysics, both employ a common two-stage methodology, the first stage of which is wholly a priori but the second stage of which is partly empirical. As I explain, appreciating this common methodology sheds new light on how the second principles are to be established, as well as on the reach of Kant’s rationalism. (shrink)

O debate acerca de qual é a natureza do conteúdo da experiência perceptiva ganhou novos contornos nas últimas décadas ao se introduzir a questão de se este conteúdo é conceitual ou não conceitual. Essa questão metafísica acerca da natureza da percepção é geralmente pressionada por uma outra de índole epistêmica: como a experiência perceptiva pode justificar crenças acerca do nosso entorno? John McDowell sustenta que, se a experiência já não tem um conteúdo conceitual de modo a apresentar o mundo como (...) sendo de uma determinada maneira, acarretando assim um elo comum entre percepção e pensamento, então é difícil ver como a experiência poderia justificar uma crença, especialmente se entendemos a justificação em termos internalistas, como faz McDowell. Contrapondo-se a essa posição, Athanassios Raftopoulos alega que se a experiência perceptiva envolve conceitos intrinsecamente e, portanto, é penetrada cognitivamente, então a experiência não é independente das nossas crenças de fundo e, desse modo, não pode funcionar como um tribunal neutro de justificação, pois o apoio evidencial fornecido pela experiência é circular e epistemologicamente viciado. Neste texto, eu defendo uma explicação de como a experiência perceptiva mantém uma relação racional com o pensamento empírico. Na primeira parte, vou elaborar duas teses que são centrais para explicar o papel de justificação da experiência perceptiva segundo uma perspectiva minimamente internalista, a saber, a tese do conteúdo comum entre a percepção e a crença e a tese da independência da percepção em relação à crença. Indicarei as dificuldades que estão envolvidas na tentativa de conciliar essas teses. A primeira parece requerer o conceitualismo de conteúdo, enquanto a segunda parece implicar sua rejeição. Apesar de declarações em contrário, eu argumento que McDowell falha em fazer justiça à segunda tese em Mind and World. Na segunda parte, apoiado na teoria enativa da percepção, de Alva Noë, defendo uma leitura menos intelectualista da primeira tese, descomprometida com o conceitualismo de conteúdo, e mostro como ela pode ser conciliada com a segunda. Finalmente, explico como atos perceptivos que nos dão acesso direto a objetos podem coagir racionalmente o pensamento empírico acerca do mundo circundante. Essa explicação pretende fazer justiça a um internalismo que qualifico como mínimo. (shrink)

I am Me and not someone else. This might just be a spur of the moment type of statement; however, it weighs more than it seems. Moreover, it delves into an individual’s understanding of the self-amidst different factors revolving one’s identity. Personal identity can be deemed as a puzzle of distinct characteristics, experiences, understanding, and values in which when put together define who a person is. It involves different aspects in life such as self-perception, cultural background, beliefs, traditions, and even (...) societal roles, which contribute bit by bit on how individuals view themselves and are perceived by others. Identity and sameness over time are related to one another. Understanding sameness over time—how a person remains essentially “the same” amidst changes in physical appearance, experiences and, or beliefs—remains significant as it helps maintain a rational sense of the self. The continuity of the interplay of changes in different aspects of an individual’s self is essential in fostering self-awareness, personal growth, and formation of stable relationship among others. This also underpins moral and legal accountability to ensure that individuals are treated as themselves throughout time. What constitutes the “self” that remains the same person over time, despite changes in experiences, physical form, and beliefs? This paper aims to explore major theories of identity and argue for the most coherent view or propose an integrated approach. (shrink)

Psychopathy refers to a range of complex behaviors and personality traits, including callousness and antisocial behavior, typically studied in criminal populations. Recent studies have used self-reports to examine psychopathic traits among noncriminal samples. The goal of the current study was to examine the underlying factor structure of the Self-Report of Psychopathy Scale–Short Form (SRP-SF) across complementary samples and examine the impact of gender on factor structure. We examined the structure of the SRP-SF among 2,554 young adults from three undergraduate samples (...) and a high-risk young adult sample. Using confirmatory factor analysis, a four-correlated factor model and a four-bifactor model showed good fit to the data. Evidence of weak invariance was found for both models across gender. These findings highlight that the SRP-SF is a useful measure of low-level psychopathic traits in noncriminal samples, although the underlying factor structure may not fully translate across men and women. (shrink)

This essay proposes that Socrates practiced various spiritual exercises, including meditation, and that this Socratic practice of meditation was habitual, aimed at cultivating emotional self-control and existential preparedness. Contemporary research in neurobiology supports the view that intentional mental actions, including meditation, have a profound impact on brain activity, neuroplasticity, and help engender emotional self-control. This impact on brain activity is confirmed via technological developments, a prime example of how technology benefits humanity. Socrates attains the balanced emotional self-control that Alcibiades describes (...) in the Symposium because of the sustained mental effort he exerts that directly impacts his brain and his emotional and philosophical life. The essay concludes that Socratic meditative practices aimed at manifesting true dignity as human beings within the complexities of a technological world offer a promising model of self-care worthy of embracing today. (shrink)